中国普通外科杂志2011,Vol.20Issue(3):265-268,4.
丹参和生脉注射液对腹腔感染并SIRS患者血清MDA和SOD的影响
Salvia Miltiorrhiza and Shengmai injection in the treatment of SIRS caused by abdominal infection, and the effect on oxygen free radicals
摘要
Abstract
Objective To evaluate the influences on oxygen free radicals of SIRS due to abdominal infection treated by Salvia Miltiorrhiza and Shengmai injection. Methods Fifty patients with SIRS due to abdominal infection were divided into 2 groups:Group A, treated by combined western medicine (n = 25 ); Group B,treated by combined western medicine plus Salvia Miltiorrhiza and Shengmai injection ( n = 25 ). Plasma malondialdehyde ( MDA ) and Superoxide dismutase ( SOD ) were measured before treatment and on day 2 and day 4 after treatment. Results The serum levels of MDA in group B decreased more rapidly than those in group A, and the serum levels of SOD in group B increased more rapidly than those in group A.Conclusions On the basis of combined westem medicine treatment, addition of Salvia Miltiorrhiza and Shengmai injection has therapeutic effect on SIRS by decreasing the harmful MDA factor and increasing the defensive SOD factors, and thereby can alleviate inflammatory injury and prevent further MODS.关键词
全身炎症反应综合征/治疗/丹参注射液/生脉注射液/丙二醛/超氧化物歧化分类
医药卫生引用本文复制引用
熊进文,黄海球,唐万兵,刘忠民,杨栋..丹参和生脉注射液对腹腔感染并SIRS患者血清MDA和SOD的影响[J].中国普通外科杂志,2011,20(3):265-268,4.基金项目
广东省深圳市科技和信息局课题(200803261). (200803261)