中国神经再生研究（英文版）2011，Vol.6Issue(4)：309-312,4.DOI:10.3969/j.issn.1673-5374.2011.04.012
Risk factors for sepsis-associated encephalopathy
Risk factors for sepsis-associated encephalopathy
摘要
Abstract
Sepsis-associated encephalopathy (SAE) is a diffuse and acute cerebral dysfunction caused by sepsis. Many sepsis patients exhibit acute deterioration in mental status during the early stage of disease, and central nervous system dysfunction has been shown to increase patient mortality. The present study selected 284 sepsis patients who were admitted to the Intensive Care Unit of Beijing Friendship Hospital, Capital Medical University, from January to December 2009. The patients were assigned to SAE and non-SAE patient groups according to SAE occurrence. SAE incidence was 37.68%, and mortality was significantly greater in SAE patients compared with non-SAE patients (41.12% vs. 17.51%, P < 0.01). Univariate analysis and multivariate logistic regression analysis indicated lower arterial partial pressure of oxygen and greater alanine aminotransferase and Acute Physiology and Chronic Health Evaluation II scores in the SAE group compared with the non-SAE group. Arterial partial pressure of oxygen, alanine aminotransferase, and Acute Physiology and Chronic Health Evaluation II scores were determined to be potential risk factors for SAE.关键词
sepsis-associated encephalopathy/incidence/mortality/risk factor/regression analysisKey words
sepsis-associated encephalopathy/incidence/mortality/risk factor/regression analysis引用本文复制引用
Jian Li,Ang Li,Yibing Weng,Shuwen Zhang,Meili Duan..Risk factors for sepsis-associated encephalopathy[J].中国神经再生研究（英文版）,2011,6(4):309-312,4.基金项目
the Natural Science Foundation of Beijing,No.7102039* （）
