中医药学报2011,Vol.39Issue(1):48-51,4.
赤芍总苷提取与大孔树脂纯化工艺研究
A Research on the Optimized Extraction Process and Macroporous Resin Purification Technology of Radix Paeoniae Rubra
摘要
Abstract
Objective: To study the optimized extraction process and macroporous resin purification technology of radix paeoniae rubra.Methods: Taking paeoniflorin as the characteristic markers, such as alcohol concentration, alcohol consumption and extraction time,which were the three factors.An orthogonal design was employed.Then selected the type of resin and investigated the adsorption velocity, resin diameter length ratio, volume of water and elution, concentration of elution and sample on the purification results.Results: The extraction with 80% ethanol 12 or 10 times as much as radix paeoniae rubra for 1.0h and twice was more effective.Extractor gets through AB - 8 macroporous resin column (diameter length ratio 1:8 ), the adsorption velocity 1 mL/min, 3 times the volume of water, 5 times the volume of 20%ethanol elution.Conclusion: The process is simple and economic, and it can be used for extraction and purification of radix paeoniae rubra.关键词
赤芍/提取/纯化/AB-8型大孔树脂分类
医药卫生引用本文复制引用
周洪伟,许文博,王玉蓉,韩振蕴..赤芍总苷提取与大孔树脂纯化工艺研究[J].中医药学报,2011,39(1):48-51,4.基金项目
国家科技重大专项课题(编号:2009ZX09103) (编号:2009ZX09103)