中医药学报2011，Vol.39Issue(1)：74-76,3.
西洋参干预胰岛素抵抗大鼠活性部位的化学成分研究Ⅳ
The Study on the Chemical Constituents of Rats' Active Site for Impacting Insulin Resistance by American Ginseng
摘要
Abstract
Objective :To study the chemical constituents of rats'active site for impacting insulin resistance by American ginseng. Methods:They were extracted by ethanol and adsorbed by macroreticular resins , then eluted with ethanol and isolated by silicagel column chromatography and HPLC preparation chromatography. Their structures were determined by physical and chemical properties , as well as spectrographical identification. Result and conclusion: Three compounds were isolated from the active site. Their structures were identified as 3 - O - β - D - glucopyranosyl - (1→2) - β - glucopyra - nosyl - 20 - O - β - glucopyranosyl - ( 1→6 ) - β - D - glucopyranosyl - dammar - 24 - ene - 3 β,12 β,20S - triol ( Ⅰ ) , 3 - O - β - D - glucopyranosyl - (1→2) - β - glucopyra - nosyl -20 - O - β - glucopyranosyl - ( 1→6) - β - D - glucopyranosyl - dammar - 24 - ene - 3 β,12 β,20R - triol ( Ⅱ ) , 3 - O - β - D - glucopyranosyl - ( 1 →2 ) - β - D - glucopyranosyl -20 - O - β - D - arabinopyranosyl - ( 1 →6) - β - D - glucopyranosyl - dammar -24 -ene- 3β,12β,20R - triol( Ⅲ ).关键词
西洋参/活性部位/胰岛素抵抗/化学成分分类
医药卫生引用本文复制引用
马育轩,葛鹏玲,杨炳友,李冀..西洋参干预胰岛素抵抗大鼠活性部位的化学成分研究Ⅳ[J].中医药学报,2011,39(1):74-76,3.基金项目
国家自然科学基金项目(编号:30672632) （编号:30672632）
黑龙江省杰出青年科学基金项目(编号:JC04-01) （编号:JC04-01）
黑龙江省博士科学基金(编号:LRB09-321) （编号:LRB09-321）
黑龙江省留学回国人员科技项目择优资助基金 （）
