首页|期刊导航|中华医学杂志（英文版）|Renal function of donors and recipients after living donor kidney transplantation in a Chinese cohort
中华医学杂志（英文版）Issue(9)：1290-1295,6.DOI:10.3760/cma.j.issn.0366-6999.2011.09.003
Renal function of donors and recipients after living donor kidney transplantation in a Chinese cohort
Renal function of donors and recipients after living donor kidney transplantation in a Chinese cohort
摘要
Abstract
Background Living donor kidney transplantation (LKT) has been booming in China. This study aimed to elucidate the renal function of both Chinese donors and recipients after the donation and transplantation.Methods One hundred and forty-one pairs of donors and recipients for LKT were randomly selected and followed up for up to seven years. The donors' and recipients' renal function was recorded before and after operation.Results The donors presented a mean age of (43.9±7.5) years at donation. The female contributed 101/141 (71.6%) in all donors, and no effect was shown between genders on healthy donors' renal function. The donors' glomerular filtration rates (GFR) were (119.5±20.4) ml/min, (85.2±17.6) ml/min, (87.2±15.9) ml/min, (82.1±14.6) ml/min and (83.0±13.7)ml/min preoperatively, and for five days, three months, one year and beyond one year after the operation. The donors for the period of 1-3 years, 3-5 years and more than 5 years after donation showed GFR as (83.9±12.7) ml/min, (83.0±17.6)ml/min, and (80.9±20.8) ml/min, respectively, no statistically significant difference was found. Moreover, no significant clinical changes in blood pressure and proteinuria were found among the donors. In the recipients, delayed graft function (DGF) rate was 6.4%, acute rejection rate was 11.3%, and GFR were (66.5±16.4) ml/min, (73.2±19.6) ml/min and (63.9±18.6) ml/min respectively at three months, one year and beyond one year post-transplantation respectively.Conclusion The donors/recipients of LKT in Chinese population experience well-functioning remaining/donor kidneys.关键词
kidney transplantation/living donors/recipient/renal functionKey words
kidney transplantation/living donors/recipient/renal function引用本文复制引用
GONG Nian-qiao,MING Chang-sheng,ZENG Fan-jun,ZHANG Wei-jie,LIN Zhen-bin,ZHOU Ping,CHEN Xiao-ping,CHEN Zhi-shui..Renal function of donors and recipients after living donor kidney transplantation in a Chinese cohort[J].中华医学杂志（英文版）,2011,(9):1290-1295,6.基金项目
This study was supported by a grant from the joint program of the Center of International Communication and Cooperation,Ministry of Health,China (No.IHECC07-001). （No.IHECC07-001）
