国际医药卫生导报2011，Vol.17Issue(5)：563-565,3.DOI:10.3760/cma.j.issn.1007-1245.2011.05.019
血清免疫球蛋白IgM和C反应蛋白联合测定对新生儿早期感染性疾病的诊断价值
Combination detection of serum immunoglobin M and C-reactive protein in the early diagnosis of neonatal infectious diseases
摘要
Abstract
Objective To explore the diagnostic value of combinatin detection of serum immunoglobin M (IgM) and C-reactive protein (CRP) for neonatal infectious diseases at the early stage.Methods Immunoturbidimetry was used to detect the serurn levels of IgM and CRP in 206 neonates with infectious diseases (infection group) and 146 with non-infectious diseases (non-infection group). Results There was no significant difference in CRP level between infection group and non-infection group (P＞0.05);whereas IgM level differed significantly between the two groups (P＜0.05). The sensitivity of CRP for infectious diseases was 96.12%, the specificity was 41.78%, and the accuracy was 73.60%; while the sensitivity ofIgM for infectious diseases was 88.29%, the specificity was 91.78% and the accuracy diseases was 89.49%. The sensitivity of combination detection was 84.86% and the specificity was 95.21%. Conclusions Combination detectinon of serum IgM and CRP can be used as an indicator for the early diagnosis of neonatal infectious diseases.diseases in newbrons. 关键词
免疫球蛋白IgM/C反应蛋白/感染性疾病/新生儿Key words
Immunoglobin M/C-reactive protein, Bacterial infection/Neonate引用本文复制引用
覃立刚,龙艳明,陈浪辉,陈天生..血清免疫球蛋白IgM和C反应蛋白联合测定对新生儿早期感染性疾病的诊断价值[J].国际医药卫生导报,2011,17(5):563-565,3.
