国际医药卫生导报2011，Vol.17Issue(5)：571-573,3.DOI:10.3760/cma.j.issn.1007-1245.2011.05.022
丙泊酚复合芬太尼或氯胺酮用于吸毒患者手术的麻醉体会
Propofol combined with fentanil or ketamine for anesthesia in drug abusers
刘端政 1尹章颂 1王旭东 2刘燕玲3
作者信息
- 1. 510430,广州,广东有司法警察医院麻醉科
- 2. 510430,广州,广东有司法警察医院普外科
- 3. 510430,广州,广东有司法警察医院手术室
- 折叠
摘要
Abstract
Objective To investigate the effect of propofol combined with fentanil or ketamine for anesthesia in drug abusers. Methods 516 drug abusers were randomly assgined to receive continuous preoperative injection of propofol of 2.5-3 mg/kg and then either intravenous fentanil of 2-3 μg/kg (258patients, group Ⅰ ) or ketamine of lng/kg (258 patients, group Ⅱ). Additional doses of fentanil or ketamine were added when necessary. Blood pressure, ECG and SpO2 were continuously monitored. Results As compared with the baseline values, MAP and HR significantly decreased in group Ⅰ (P＜ 0.05), while increased in group Ⅱ (P＜0.05); there was no significant difference in SpO2. No abstinent symptoms occurred in all the patients. Conclusions Propofol combined with fentanil or ketamine can not only prevent and treat abstinent symptoms but also enhance anesthestic effect. lntraoperative monitoring should be enhanced and the stability of respiration and circulation system should be maintained.关键词
药物依赖/丙泊酚/芬太尼/氯胺酮Key words
Drug abuse/Propofol/Fentanil/Ketamine引用本文复制引用
刘端政,尹章颂,王旭东,刘燕玲..丙泊酚复合芬太尼或氯胺酮用于吸毒患者手术的麻醉体会[J].国际医药卫生导报,2011,17(5):571-573,3.
