摘要
Abstract
Objective To study impaired fasting glucose ( IFG ) in hypertensive patients insulin resistance and Pancreatic β cell function status. Methods 94 cases of out-patients with hypertension,according to glucose tolerance group were divided into normal glucose tolerance( NGT n = 35 ), IFG group of 31 cases, type 2 diabetes( T2DM group )in 28 cases. Blood pressure, height, weight, waist circumference,hip circumference, blood lipids, fasting and 2 hours after glucose load blood glucose and insulin and other parameters, weight and body mass index, waist hip ratio, pancreatic β cell function index ( FINS, FBCI,after the glucose load net increase of 30 minutes, the ratio of glucose, insulin and a net increase( ? I30/?G30 ), HOMA-IS ), insulin resistance index ( IAI, HOMA-IR )were all conducted and analyzed and as well as the statistical comparison between each group. Results Cardiovascular risk factors such as obese or overweight, increased waist-hip ratio, lipid metabolism disorders were gathered in all groups in hypertensive patients; meanwhile, IFG group and the T2DM group diastolic blood pressure higher than NGT group; IFG group and the T2DM group LDL-C, TG level higher than the group with NGT, T2DM group HLDL-C less than the NGT group; Three groups of IAI ( -3.26 ± 0.62 ), ( -3.61 ± 0.68 ), ( -4.01 ±0.77 ), HOMA-IR ( 0.67 ± 0.46 ), ( 0.92 ± 0.53 ), ( 1.01 ± 0.52 ), HOMA-IS ( 4.87 ± 1.35 ), ( 4.关键词
空腹血糖受损/高血压病/胰岛β细胞功能Key words
Impaired fasting glucose/Hypertension/Islet β-cell function
