实用医学杂志2011，Vol.27Issue(7)：1275-1277,3.DOI:10.3969/j.issn.1006-5725.2011.07.060
中国大肠埃希菌头孢他啶耐药趋势规律的IMMI推测应用研究
Study on the prediction of trend and regularity of the ceftazidime-resistance of E.coli in China using the IMMI method
丁凡 1李怡 2栾进3
作者信息
- 1. 100097,北京市,武警森林指挥部卫生处
- 2. 100035,北京市,武警北京总队第二医院心内科
- 3. 102600,北京市,武警疾病预防控制中心
- 折叠
摘要
Abstract
Objective To assess the application potential of the improved MMI (IMMI) to analyze the trend and regularity of ceftazidime-resistance of E.coli in China. Methods The puhlished data of drug-resistance of E.coli to Ceftazidime was collected from the China national knowledge internet (CNKI) during the period from 1996 to 2009. The annual mean drug-resistance data was analyzed by the X2 trend test and presumed by the IMMI method, IMMI presumed results and the comparations of the presumed results from IMMI and MMI were mainly by sum of squares of error (SSE) , relative standard error (RSE) and mean ahsolute deviation (MAD) methods. Results The annual mean drug-resistance data analyzed by the X2 trend test showed an escalating trend (P ＜ 0.01). The IMMI assay revealed that SSE, RSE and MAD value closed to the smallest level when H equaled to 1.Data analysis hetween IMMI and MMI methods showed that, IMMI (H = 0.01) showed smallest value in the SSE, RSE and MAD value based-on IMMI method (H = 0.01) were smaller than those based-on MMl method (M = 2, K = 2/3). Conclusion The prediction result hase-on IMMI (H = 0.01) method is better than that based-on MMI (M = 2, K = 2/3) method. The IMMI (H = 0.01) analysis showed that the drugresistance data of E.coli to Ceftazidime was influenced mainly by the short-term data and was influenced little by the long-term data. Both MMI and IMMI are available methods for prediction the Ceftazidime-resistance of E.coli, however, the IMMI method is better, and the results would be influenced obviously by different parameter setting in both IMMI and MMI methods.关键词
药物耐受性/MMI改良法/埃希氏菌属/头孢他啶引用本文复制引用
丁凡,李怡,栾进..中国大肠埃希菌头孢他啶耐药趋势规律的IMMI推测应用研究[J].实用医学杂志,2011,27(7):1275-1277,3.
