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凝聚法检测D-二聚体在诊断急性肺栓塞中的临床应用

刘宇 周荣斌

中国全科医学2011,Vol.14Issue(13):1447-1448,2.
中国全科医学2011,Vol.14Issue(13):1447-1448,2.

凝聚法检测D-二聚体在诊断急性肺栓塞中的临床应用

Coagulation Test for D-dimer in Clinical Diagnosis of Acute Pulmonary Embolism

刘宇 1周荣斌1

作者信息

  • 1. 100700,北京市,北京军区总医院急诊科
  • 折叠

摘要

Abstract

Objective To evaluate the efficacy of D - dimer coagulation test reagent in the exclusion of acute pulmonary emholism ( APE ) . Methods A Self - controlled trial design was adapted. Totally 91 patients who needed an exclusion of APE were tested with British BB International D - dimer test kit ( trial reagent ) and Shanghai Jiemen's D - dimer kit ( control reagent ) respectively. If the results on the two reagent samples were inconsistent, the third kit ( colloidal gold method ) would be used to verify the correctness. And the positive and negative coincidence rates, as well as the sensitivity and specificity of the two groups were observed. Results BB International reagent detected 28 positive cases and 63 negative cases; with a positive consistent rate of 100. 0% and a negative coincidence rate of 84. 0% ; Shanghai Jiemen reagent detected 16 positive cases and 75 negative cases. According to the verification by the third kit, the sensitivity and specificity of BB International reagent were 100. 0% and 96. 9% respectively. Conclusion D - dimer coagulation test reagent is suitable for rapid auxiliary diagnosis for exclusion of acute pulmonary embolism.

关键词

肺栓塞/D-二聚体/凝聚法

分类

医药卫生

引用本文复制引用

刘宇,周荣斌..凝聚法检测D-二聚体在诊断急性肺栓塞中的临床应用[J].中国全科医学,2011,14(13):1447-1448,2.

中国全科医学

OA北大核心CSTPCD

1007-9572

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