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胃液及血清CA724,CA199和CEA联合检测对胃癌诊断的意义

何思春 庞红全 焦鑫 王利君 刘兴琼

现代检验医学杂志2011,Vol.26Issue(2):117-119,3.
现代检验医学杂志2011,Vol.26Issue(2):117-119,3.DOI:10.3969/j.issn.1671-7414.2011.02.041

胃液及血清CA724,CA199和CEA联合检测对胃癌诊断的意义

Clinical Significance of Combined Measuring Gastric Juice and Blood Serum's CA724,CA199 and CEA for Gastric Cancer Diagnosis

何思春 1庞红全 1焦鑫 1王利君 1刘兴琼1

作者信息

  • 1. 四川省达州市中心医院,四川达州,635000
  • 折叠

摘要

Abstract

Objective To investigate the clinical value of cancer antigen-724(CA724),cancer antigen-199(CA199) and carcinoembryanic antigen(CEA) tests with a combined style for gastric cancer and benign gasrrosia. Methods The levels of CA724 ,CA199 and CEA in gastric juice and blood serum were detected by using electrochemiluminescence (ECL). Results Compared with benign gastrosia, there weresignificant deviation in the positive rate of CEA ,CA199 and CA724 in gastric patients , gastric juice and blood serum. Combination detection sensitivity of blood serum and gastric juice was the highest in the parallel experiment (78. 6% );and the sequence experiment showed that two items or above positive markedly increased the diagnostic specificity. Conclusion The combined detection of CA724,CA199 and CEA could improve diagnosis sensitivity for gastric cancer,and two items or above positive could improve diagnosis specificity for gastric cancer.

关键词

胃癌/胃液/血清/CA724/CA199/CEA

分类

医药卫生

引用本文复制引用

何思春,庞红全,焦鑫,王利君,刘兴琼..胃液及血清CA724,CA199和CEA联合检测对胃癌诊断的意义[J].现代检验医学杂志,2011,26(2):117-119,3.

现代检验医学杂志

OACSTPCD

1671-7414

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