中国畜牧兽医2011，Vol.38Issue(2)：84-87,4.
悬液芯片系统在检测领域的研究进展
Research Advances on Suspension Assay System and its Application in Detection
摘要
Abstract
In the mid-1990s, the Luminex Corporation(USA) exploited the first suspension array system, which used fluorescent-coded carboxytic beads as solid carrier. Proteins, oligonucleotides, small peptides and lipids have been adsorbed or chemically coupled to the surface of microspheres to format detected probe. According to the different proportion of red and orange fluorescent dyes inside beads, the beads are divided into 100 different types. The intensity of fluorescent associated with beads and fluorescent probe are tested simultaneously by special detector on suspension array system. The detector can distinguish beads of different types basing on different proportion of two fluorescent dyes while recording the intensity of fluorescent from probe on every bead to achieve high throughput detection. This article reviews the research regarding suspension assay system and its application in detection.关键词
悬液芯片系统/蛋白质/核酸/检测分类
生物科学引用本文复制引用
刘天龙,王燕飞,邹明强,刘小雷,云彩麟..悬液芯片系统在检测领域的研究进展[J].中国畜牧兽医,2011,38(2):84-87,4.基金项目
国家自然科学基金项目(20875084/B0509). （20875084/B0509）
