摘要
Abstract
Objective To examine the relation between HP infection and acute coronary syndrome( ACS ). Methods HPIgG were measured in total 106 cases of ACS( acute myocardial infarction 57 cases ,unstable angina pectoris 49 cases )and 61 nomal controls by ELISA, through which HP Infection can can diagnosed. High sensitivity C-reactive protein ( hsCRP ),fibrinogen( FIB ),interleukin-6( IL-6 )were measured in 106 cases of ACS. Results The rate of seropositive for HPIgG in acute myocardial infarction group and unstable angina pectoris group was significantly higher than that of controls ( P ＜0.01 );these was no correlation between HP infection and hypertension,diabetes mellitus ,obesity, smoking ,age ,gender and family medical history ;the level of hsCRP in these of HPIgG seropositivity in ACS group was considerably higher than that of HPIgG seroneative in ACS group ( P ＞ 0.05 ); the level of IL-6 and FIB in these of HPIgG seropositivity in ACS group was apparently higher than that of HPIgG seronegative in ACS group( P ＜ 0.05 ). Conclusion There is certain relation between HP infection and acute coronary syndrome. HP infection may act though raising the level of hsCRP, IL-6 and FIB.关键词
急性冠脉综合征/幽门螺杆菌/白细胞介素-6/超敏C反应蛋白/纤维蛋白原Key words
Acute coronary syndrome/ Helicobacter Pylori/ Interleukin-6/ High sensitivity C-reactive protein/Fibrinogen分类
医药卫生
