摘要
Abstract
Objective To investigate the epidemiology, etiology, and prognosis of hospital - acquired acute renal failure. and to compare them with those of community - acquired acute renal failure. Methods 269 patients confirmed with ARF in our hospital from January 2001 to December 2008 were divided into hospital - acquired ARF group and community - acquired ARF group according to ARF occurred in hospital or community. The epidemiology , etiology , complication and prognosis of the two groups were analyzed. Results Among all the inpatients, ARF accounted for 0. 14％ from January 2001 to December 2004 and 0. 12％ from January 2005 to December 2008. 36 patients died from 2001 to 2004. the mortality rate was 32. 4％ ,while 48 patients died from 2005 to 2008 . the mortality rate was 30. 4％ . The difference between the mortality rate was not statistically significant ( P ＞ 0. 05 ). 32cases ( 45. 7％ ) of HA - ARF were diagnosed in department of surgery , compared with 33 cases ( 16. 6％ ) of CH - ARF, there was a statistically significant difference ( P ＜ 0. 001 ). Drugs ( 27 . 38. 6％ ), low renal perfusion ( 24, 34. 3％ ), infections ( 5, 7. 1％ ) were the major causes for the development of HA - ARF, whose causes were more concentrated than those of CA - ARF [ drugs ( 34, 17. 1％ ), calculus ( 29, 14. 6％ ), low renal perfusion ( 28,14. 1％ ), infections ( 14, 7. 0％ ), malignancies ( 14, 7. 0％ ), nephrotic syndrome ( 14, 7. 0％), glomerular nephritis ( 10, 5. 0％ ), toxis ( 6, 3. 0％ ) ]. The incidence of infection and respiratory failure were significantly higher in HA - ARF group than in CA - ARF group ( HA - ARF: CA - ARF① infection 32. 9％ : 16. 1％ ② respiratory 15. 7％ : 4. 0％ ). Mortality in HA - ARF group ( 10, 14. 3％ ) was significantly higher than that of CA - ARF group ( 10, 5. 0％ ) ( P ＜0. 05 ). Conclusion Incidence and mortality of ARF do not decrease significantly with the development of medical level in recent years. The major causes of HA - ARF are mainly low renal perfusion and drugs. Compared with CA - ARF, HA - ARF is more likely to happen in department of surgery and is more likely to complicate infection and respiratory with a higher mortality.关键词
肾衰竭/流行病学/病因学/预后/医院获得性分类
医药卫生
