中国病理生理杂志2011，Vol.27Issue(4)：653-657,5.DOI:10.3969/j.issn.1000-4718.2011.04.006
不同周龄自发性高血压大鼠动态血压变化及阻力血管形态学研究
Changes of ambulatory blood pressure and morphology of resistance vessel in spontaneously hypertensive rats at different weeks of ages
摘要
Abstract
AIM : To observe the changes of amhulatory blood pressure and morphology of resistance vessel in spontaneously hypertensive rats ( SHR) at different weeks of ages.METHODS : SHR at the ages of 16 - week and 40- week were used.The blood pressure ( BP) was monitored by radiotelemetric technique ( RTT).The data of BP. diurnal variation and the variability were analyzed.RESULTS : The results showed that the falling rate of BP at night in 16 - week group was larger than that in 40 - week group (0.0498 vs 0.0211 , P ＜ 0.05 ) .The BP variability in 40 weeks group was higher than that in 16 - week group.Tunica media area/lumen area ratio of arteria mesenterica was mcreased with aging ( P ＜ 0.05 ) .CONCLUSION: The variability of 24 - hour blood pressure in 40 - week - old SHR is higher than that in 16- week - old SHR.Along with the increase in ages, tunica media vasorum area/lumen area m resistance blood vessel ( arteria mesenterica) increases.关键词
自发性高血压大鼠/动态血压/高血压分类
医药卫生引用本文复制引用
李虹,肖传实,王蕾,杨慧宇..不同周龄自发性高血压大鼠动态血压变化及阻力血管形态学研究[J].中国病理生理杂志,2011,27(4):653-657,5.基金项目
山西省卫生厅科技攻关基金资助项目(No.200818) （No.200818）
