中国组织工程研究与临床康复2011，Vol.15Issue(11)：2059-2063,5.DOI:10.3969/j.issn.1673-8225.2011.11.040
胚胎发育与环境激素的影响
Effects of environmental hormone on embryonic development
摘要
Abstract
BACKGROUND: Many studies have shown that the increasing occurrence of reproductive abnormalities in wild life may be associated with exposu re to environmental hormone. With the pollution of the environment, effects of environmental hormone on embryonic development have been paid more and more attention.OBJECTIVE: To review the effects and possible mechanism of various environmental hormone on the process of embryo implantation, embryonic development during preimplantation and the development of embryonic reproductive system.METHODS: CNKI database and Pubmed database were searched using key words of "environmental hormone and diethylstilbestrol, mifepristone, methoxychlor, bisphenol A, tetrachlorodibenzo-p-dioxin, embryonic development, early embryonic development", for papers add ressing the effects of environmental hormone on embryonic development.RESULTS AND CONCLUSION: Totally 45 articles were adapted. Common environmental hormones widely spread in daily life in a great variety. Different environmental hormones have synergistic reaction. The mechanism exploration is at the step stage. It is necessary to control production source of environmental hormones and reduce anthropogenic discharge to decline the effect of environmental hormones on human healthy.关键词
环境激素/己烯雌酚/米非司酮/甲氧滴滴涕/双酚A/早期胚胎发育/着床分类
基础医学引用本文复制引用
胡梦桑,陈毅斐,徐营..胚胎发育与环境激素的影响[J].中国组织工程研究与临床康复,2011,15(11):2059-2063,5.基金项目
浙江省实验动物平台计划项目(2008F80025)、嘉兴市科研项目(2010AY1098)和浙江省大学生科技创新活动计划(新苗人才计划)项目(851910104)资助. （2008F80025）
