重庆医学2011，Vol.40Issue(14)：1397-1398,2.DOI:10.3969/j.issn.1671-8348.2011.14.018
埃索美拉唑与奥美拉唑治疗内镜黏膜下剥离术术后并发症的对比观察
Comparison of endoscopic submucosal dissection postoperative complications treated with esomeprazole and omeprazole
杨均 1余建华 2肖潇 1孙文静 1沈小春 1傅鑫 1邢寒阳 1胡辂1
作者信息
- 1. 第三军医大学大坪医院消化内科,重庆,400042
- 2. 重庆市綦江县人民医院内科,401420
- 折叠
摘要
Abstract
Objective To compare the therapeutic effect of the endoscopic submucosal dissection(ESD) postoperative complications treated with esomeprazole and omeprazole. Methods 20 patients with ESD were randomized to observation group with 21 cases and control group with 41 cases. The observation group was administered esomeprazole(40mg twice a day), omeprazole(40mg twice a day)for 7 d. The therapeutic effct of each drug such as auound surface healing and their symptoms such as stomachache,perforation and adverse reaction were observed. Results There was no statstic difference between both of the groups in the degree of the stomachache release(P＞0.05). There was statistic difference between both of the groups in wound surface healing after 7 dpostoperation(P＜0.05), but there was no difference after postoperative 14 d (P＞ 0. 05). Less adverse reaction was observed in both groups. Conclusion Effects of esomeprazole can promote the earlier healing of wound surface after ESD.关键词
奥美拉唑/手术后并发症/内镜黏膜下剥离术/上皮内瘤变,胃早癌/埃索美拉唑Key words
omeprazole/ postoperative complications/ endoscopic submucosal dissection/ intraepithelial neoplasia, early gastric cancer/ esoprazole引用本文复制引用
杨均,余建华,肖潇,孙文静,沈小春,傅鑫,邢寒阳,胡辂..埃索美拉唑与奥美拉唑治疗内镜黏膜下剥离术术后并发症的对比观察[J].重庆医学,2011,40(14):1397-1398,2.
