中国脑血管病杂志2011，Vol.8Issue(2)：60-64,5.DOI:10.3969/j.issn.1672-5921.2011.02.002
单中心动脉溶栓治疗急性缺血性卒中576例的疗效分析
Intra-arterial thrombolysis for 576 cases of acute ischemic stroke: a single center analysis
王亚冰 1缪中荣 1焦力群 1李慎茂 1朱凤水 1吉训明 1凌锋1
作者信息
- 1. 100053,北京,首都医科大学宣武医院介入放射诊断治疗科
- 折叠
摘要
Abstract
Objective To investigate the safety and efficacy of intra-arterial thrombolysis in the treatment of acute ischemic stroke. Methods The clinical data of the patients in the Department of Interventional Radiology, Xuanwu Hospital, Capital Medical University from January 2000 to September 2010 were analyzed retrospectively. A total of 576 patients with acute ischemic stroke were treated with intra-arterial thromboysis, 160 patients were female and 416 were male, their mean age was 55 ± 10 years old.The therapeutic time windows of anterior and posterior circulation lesions were 5. 1 ± 1.8 and 9. 1 ± 2. 2 h respectively , and the dosages of urokinase were 82 ± 21 and 104±15 Urespectively. Results ①389patients had internal carotid arterial occlusion, their recanalization rate was 61.7％, and 68 patients were conducted with laser-assisted balloon dilation or stent placement. The improvement rate of mRS was 66. 1％2 weeks after thrombolysis, and the symptomatic intracranial hemorrhage rate was 13. 3％. ②101 patients had vertebral-basilar arterial occlusion, the recanalization rate was 64. 3％. Thirty patients were conducted with laser-assisted balloon dilation or stent placement. The improved rate of mRS was 43.6％ 2 weeks after thrombolysis, and the symptomatic intracranial hemorrhage rate was 5. 0％. ③Cerebral angiography was negative in 86 patients, accounting for 14. 9％ of all the cases. Conclusion After thrombolysis of extracranial and intracranial arterial occlusion, the rate of recanalization, the improved rate of mRS, and the rate of symptomatic intracranial hemorrhage showed that arterial thrombolysis in the treatment of acute ischemic stroke is a relatively safe and effective method of treatment.关键词
脑血管障碍/脑缺血/血栓溶解疗法/注射,动脉内引用本文复制引用
王亚冰,缪中荣,焦力群,李慎茂,朱凤水,吉训明,凌锋..单中心动脉溶栓治疗急性缺血性卒中576例的疗效分析[J].中国脑血管病杂志,2011,8(2):60-64,5.
