中国组织工程研究与临床康复2011,Vol.15Issue(12):2187-2191,5.DOI:10.3969/j.issn.1673-8225.2011.12.024
Onyx胶栓塞脑动静脉畸形31例
Embolization of cerebral arteriovenous malformation with Onyx in 31 cases
摘要
Abstract
BACKGROUND: As for the endovascular embolization treatment of cerebral arteriovenous malformations, the embolic materials play a greatly decisive role on the therapeutic effect. Onyx is a new liquid embolic agent developed in recent years, with non-stick tube, dispersion uniformity and good controllability.OBJECTIVE: To summarize the embolization techniques and clinical efficacy of cerebral arteriovenous malformation by using a new liquid embolic agent (Onyx).METHODS: Thirty-one patients with cerebral arteriovenous malformation were treated with Onyx, 6F sheath inserted into femoral artery using Seldinger technique followed by 6F guiding catheter introduced into the internal carotid artery or vertebral artery,Marathon micro-catheter could be navigated into the nidus of arteriovenous malformation, then the Onyx was injected slowly into the cerebral arteriovenous malformation with "inject-back flow-stop-reinject" technique.RESULTS AND CONCLUSION : 40%-60% embolizations were achieved in 8 cases, 60%-90% in 7 cases, more than 90% (complete embolization) in 16 cases. Among 15 cases of incomplete embolization, 4 underwent surgical removal including 3 cases with good outcome and 1 case of hemiplegia with muscular strength of degree Ⅳ; 6 cases were treated by γ -knife after embolization, 2 cases of them showed complete occlusion after radiosu rgery. Onyx has unique and distinctive superiority in treating cerebral arteriovenous malformations. However, the embolization techniques should be well trained to get good results and avoid complications.关键词
动静脉畸形/Onyx胶/血管内栓塞治疗/并发症/生物材料分类
基础医学引用本文复制引用
唐景峰,王文波,黄永旺,杨保华,杜贻庆,莫万彬,阳永东,夏学巍,唐乐剑,周晓坤..Onyx胶栓塞脑动静脉畸形31例[J].中国组织工程研究与临床康复,2011,15(12):2187-2191,5.基金项目
广西壮族自治区卫生厅资助课题(Z2008264),课题名称:脑血管畸形血管内治疗的临床研究 (Z2008264)