国际眼科杂志2011，Vol.11Issue(5)：760-764,5.DOI:10.3969/j.issn.1672-5123.2011.05.003
儿童早期复发型视神经脊髓炎的成功治疗1例
Successful treatment of an early recurrence of neuromyelitis optica in a child
Wai Seng Chiang 1Terrence Thomas 2Tat Way Leslie Wong 3Shuaibah Abdul Ghani 3Mohtar Ibrahim1
作者信息
- 1. 马来西亚吉兰丹州,邦阁亮区16150,马来西亚理科大学医学院眼科
- 2. 马来西亚沙巴州,Kota,Kinabalu,88996,沙巴州妇女儿童医院儿科
- 3. 马来西亚沙巴州,Kota,Kinabalu,88200,伊利沙伯医院眼科
- 折叠
摘要
Abstract
AIM:To report unusual presentation and good outcome of neuromyelitis optica(NMO) in a child.METHODS:Case Report.RESULTS: An 8-year-old girl presented with 5-day history of sudden bilateral visual deterioration followed by left lower limb weakness. Visual acuity was perception to light in both eyes. Funduscopy revealed bilateral hyperaemic swollen optic discs. MRI of brain and spine revealed enhancing white matter lesions in the right frontal lobe and spinal cord at C5 level. She was diagnosed NMO and treated with intravenous methylprednisolone and tapering doses of oral prednisolone as maintenance therapy.Symptoms gradually improved 1 month after treatment. However, she presented with similar presentation 1 week after stopping oral prednisolone. MRI of brain and spine were reviewed and showed enhancing lesion in the right frontal lobe and longitudinal segment of spinal cord from C3 to C5 level. She was promptly given intravenous methylprednisolone for 5 days followed by prolonged tapering of oral prednisolone over 6 months period. After 2 months, she was able to walk and attend activities of school. Visual acuity was improved to 6/10 in both eyes and neurological examination was normal. There was no recurrence during the next year. Final visual acuity was 6/7.5 in the the right eye and 6/10 in the left eye.CONCLUSION: The diagnosis of NMO should be kept in mind although it is unusual presentation in child presented with bilateral visual loss and unilateral lower limb weakness. Early diagnosis and treatments would yield good outcome to the patient.关键词
视神经脊髓炎/视神经炎/脊髓炎/儿童Key words
neuromyelitis optica/optic neuritis/myelitis/children引用本文复制引用
Wai Seng Chiang,Terrence Thomas,Tat Way Leslie Wong,Shuaibah Abdul Ghani,Mohtar Ibrahim..儿童早期复发型视神经脊髓炎的成功治疗1例[J].国际眼科杂志,2011,11(5):760-764,5.
