siRNA转染肝癌HepG2细胞Survivin基因凋亡机制探讨OACSTPCD

Objective: The aim of this study was to investigate the molecular mechanism of anti-apoptotic action of survivin to the hepatoma-cellular carcinoma cell line HepG2. Methods: Design and synthesize siRNA gene sequence specifically targeting at HepG2 cell. HepG2 cells cultures were divided into five groups: blank control group, negative control group, low dose group, medium dose group and high dose group. HepG2 cells were treated respectively by pshRNA-survivin…查看全部>>