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种植窗期HB-EGF与IVF-ET妊娠结局关系的研究

宋梦玲 徐仙 刘春莲 刘蔚 赵君利 马小红 李永丽

实用妇产科杂志2011,Vol.27Issue(2):124-126,3.
实用妇产科杂志2011,Vol.27Issue(2):124-126,3.

种植窗期HB-EGF与IVF-ET妊娠结局关系的研究

Relationship between Heparin-binding Epidermal Growth Factor in the Implantation Window and the Outcome of In Vitro Fertilization and Embryo Transfer

宋梦玲 1徐仙 1刘春莲 1刘蔚 1赵君利 1马小红 1李永丽1

作者信息

  • 1. 宁夏医科大学附属医院,宁夏回族自治区生殖与遗传重点实验室,生育力保持省部共建教育部重点实验室,宁夏,银川750004
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摘要

Abstract

Objective: To study the relationship of endometrial heparin-binding epidermal growth factor (HB-EGF) in the pregnancy outcome of in vitro fertilization and embryo transfer(IVF-ET).Methods: The endometrial tissue samples were obtained from 56 patients undergoing IVF-ET firstly in the implantation window from Oct 2009 to April 2010.The endometrial HB-EGF in implantation window was detected by real-time Quantitative PCR.56 patients were divided into the pregnancy group (23 patients) and non-pregnancy group (33 patients).Results: The quantity of endometrial HB-EGF in implantation was higher in pregnancy group than that in non-pregnancy group (2.39 ±0.60 vs 1.14 ±0.61, P <0.05).Conclusions: The expressions of endometrial HB-EGF in the implantation window can be used to predict IVF-ET outcome.

关键词

肝素结合性表皮生长因子/种植窗期/体外受精-胚胎移植/妊娠

分类

医药卫生

引用本文复制引用

宋梦玲,徐仙,刘春莲,刘蔚,赵君利,马小红,李永丽..种植窗期HB-EGF与IVF-ET妊娠结局关系的研究[J].实用妇产科杂志,2011,27(2):124-126,3.

基金项目

宁夏生殖与遗传重点实验室开放课题(项目编号:SY200808) (项目编号:SY200808)

实用妇产科杂志

OA北大核心CSCDCSTPCD

1003-6946

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