中国组织工程研究与临床康复2011,Vol.15Issue(18):3243-3246,4.DOI:10.3969/j.issn.1673-8225.2011.18.004
活体肝移植中轻度脂肪变性供肝的应用
Steatotic liver in donor for living related liver transplantation
摘要
Abstract
BACKGROUND: Steatotic liver graft transplantation affects donor safety as well as recipient survival in living related liver transplantation (LRLT).OBJECTIVE: To assess safety of donors of steatotic liver and prognosis of steatotic liver grafts' recipients in LRLT.METHODS: We retrospectively reviewed 104 cases of LRLT, dividing them into 4 groups according to degree of macrovesicular fatty change upon intraoperative liver biopsy. The degree of macrovesicular steatosis was compared among four groups, and death cause was analyzed among 104 cases undergoing right liver transplantation.RESULTS AND CONCLUSION: There was no statistically significant difference in postoperative hepatic function recovery of donors and recipients among four groups. Overall recipients' prognosis was not different among the groups. No primary graft nonfunction (PNF) or delayed graft function (DGF) occurred. Mild macrovesicular steatotic livers may be good donor candidates without significant complications as long as sufficient residual liver volume is left for the donor. Mild macrovesicular steatotic graft did not increase the risk of graft dysfunction or morbidity in LRLT关键词
脂肪变性供肝/活体肝移植/评估/肝硬化/肝功能分类
医药卫生引用本文复制引用
崔子林,傅志仁,朱志军,张雅敏,张建军,蒋文涛,杨涛,李淮明生,张威..活体肝移植中轻度脂肪变性供肝的应用[J].中国组织工程研究与临床康复,2011,15(18):3243-3246,4.基金项目
China Medical Board in New York(06837). (06837)