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阿魏胶囊的急性毒性实验研究

张海英 薛洁 田锋

中国药业2011,Vol.20Issue(11):5-6,2.
中国药业2011,Vol.20Issue(11):5-6,2.

阿魏胶囊的急性毒性实验研究

Experimental Study on Acute Toxicity of Awei Capsule

张海英 1薛洁 1田锋2

作者信息

  • 1. 新疆医科大学附属中医医院,新疆,乌鲁木齐,830000
  • 2. 四川天然药物研究所,四川,成都,610041
  • 折叠

摘要

Abstract

Objective To perform the acute toxicity tests by gavaging Awei Capsule in mice to observe its safety and further to provide the basis for clinical medication. Methods The experimental mice were gavaged with Awei Capsule. The half lethal dose (LD50) was determined by the trial test and according to this, the maximum tolerated dose(MTD) was determined. Results LD50 was not detected.The largest administration amount within 1 d in mice was 9.888 g, which was equivalent to 360 times of clinical adult daily dosage. Conclusion Awei Capsule has low toxicity, which is safe and reliable to be taken at the prescribed dose.

关键词

阿魏胶囊/急性毒性试验/半数致死量/最大耐受量

分类

医药卫生

引用本文复制引用

张海英,薛洁,田锋..阿魏胶囊的急性毒性实验研究[J].中国药业,2011,20(11):5-6,2.

基金项目

新疆维吾尔自治区卫生厅中医民族医药青年科技人才专项课题,项目编号:2009ZMY03. ()

中国药业

OACSTPCD

1006-4931

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