中国组织工程研究与临床康复2011，Vol.15Issue(18)：3371-3375,5.DOI:10.3969/j.issn.1673-8225.2011.18.035
细胞凋亡与肝移植缺血再灌注损伤
Apoptosis and ischemia-reperfusion injury following liver transplantation
吴勤荣 1时军 1王永刚1
作者信息
- 1. 江西省人民医院,江西省南昌市330006
- 折叠
摘要
Abstract
BACKGROUND: Liver transplantation has become an effect means for end-stage liver disease. Hepatic ischemia-reperfusion injury is an important factor to influence the effects of liver transplantation. Cell apoptosis is one of important mechanisms for transplanted liver ischemia reperfusion injury OBJECTIVE: To provide references for the clinical application of anti-apoptosis treatment in relieving organ ischemia-reperfusion injury based on recent studies about apoptosis and transplanted liver ischemia-reperfusion injury.METHODS: The databases of PubMed (http://www.ncbi.nlm.nih.gov/PubMed) and CNIKI (http://dlib.cnki.net/kns50/) were retrieved by the first author with key words of "apoptosis, organ transplantation, ischemia-reperfusion injury" in both Chinese and English from 1990 to 2010. The repetitive studies were excluded. Totally 339 articles were gotten by computers according to criteria, 39 articles of which were included in the final analysis.RESULTS AND CONCLUSION : There is close relationship between the apoptosis and liver ischemia-reperfusion injury. And inhibiting cell apoptosis can effectively reduce the liver ischemia-reperfusion injury, which will play an important role for the graft survival.关键词
细胞凋亡/肝移植/缺血再灌注损伤/存活率/综述文献分类
医药卫生引用本文复制引用
吴勤荣,时军,王永刚..细胞凋亡与肝移植缺血再灌注损伤[J].中国组织工程研究与临床康复,2011,15(18):3371-3375,5.
