中国临床药理学与治疗学2011，Vol.16Issue(2)：200-203,4.
氟伐他汀对高脂血症伴冠心病患者的临床疗效评价
Effects of fluvastatin on exercise-induced myocardial ischemia in patients with stable exertional angina pectoris and hypercholesterolemia
霍永佳1
作者信息
- 1. 贵阳肺科医院心内科,贵阳550002,贵州
- 折叠
摘要
Abstract
AIM: To investigate the effects of fluvastatin on myocardial ischemia induced by exercise testing in patients with stable exertional angina pectoris and hypercholesterolemia.METHODS: Ninety patients with stable exertional angina pectoris, positive exercise test and hypercholesterolemia were randomly divided into a 12-week treatment period either diet plus fluvastatin (n=45) or diet alone(n=45). All the patients underwent exercise testing before and after the treatment period. RESULTS:Fluvastatin -treated patients had a significant decrease in total cholesterol, triglyccrides, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol after treatment ( P ＜ 0.05). After treatment, the patients in the fluvastatin group had significantly increase in exercise tolerance,longer time in ST depression of 1.0 mm and decrease in the severity of ST depression. CONCLUSION: Fluvastatin can reduce exercise-induced myocardial ischemia in patients with stable exertional angina pectoris and hypercholesterolemia.关键词
氟伐他汀/心绞痛/运动试验/高脂血症分类
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霍永佳..氟伐他汀对高脂血症伴冠心病患者的临床疗效评价[J].中国临床药理学与治疗学,2011,16(2):200-203,4.
