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首页|期刊导航|中国美容医学|烧伤创面内表皮生长因子与表皮生长因子受体蛋白变化的临床研究

烧伤创面内表皮生长因子与表皮生长因子受体蛋白变化的临床研究

谷廷敏 隋志甫 常冬青 石成方 赵志力

中国美容医学2011,Vol.20Issue(3):414-416,3.
中国美容医学2011,Vol.20Issue(3):414-416,3.

烧伤创面内表皮生长因子与表皮生长因子受体蛋白变化的临床研究

Clinic study on the endogenous changes of EGF and EGFr in the bum wound

谷廷敏 1隋志甫 1常冬青 1石成方 1赵志力1

作者信息

  • 1. 北京军区总医院皮肤激光整形美容中心,北京,100125
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摘要

Abstract

Objective To observate the change and the distribution of endogenous epidermal growth factor (EGF) and epidermal growth factor recepter (EGFr) in the burn wound and their effects on the wound healing. Methods The immunohistochemistry stainning method is used to detect the expression of EGF and EGFr in the different parts of burn wound in 35 patients. Results There are more remarkably expression of EGF and EGFr in the margin part between the granulation part and the healed part of the burn wound and with obviously expression of EGF and EGFr in the center granulation part and with slightly expression of EGF and EGFr in the healed reepithelization part of the wound. Conclusion The changes of endogenous EGF and EGFr in the burn wound are closely related to the wound healing and which may have an important role effects on wound healing.

关键词

烧伤创面/表皮生长因子/表皮生长因子受体/免疫组织化学

Key words

burn wound/epidermal growth factor receptor(EGFr)/epidermal growth factor (EGFr)/ immunohistochemistry

分类

医药卫生

引用本文复制引用

谷廷敏,隋志甫,常冬青,石成方,赵志力..烧伤创面内表皮生长因子与表皮生长因子受体蛋白变化的临床研究[J].中国美容医学,2011,20(3):414-416,3.

基金项目

国家自然科学基金资助课题(30973123) (30973123)

中国美容医学

1008-6455

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