中国美容医学2011,Vol.20Issue(3):414-416,3.
烧伤创面内表皮生长因子与表皮生长因子受体蛋白变化的临床研究
Clinic study on the endogenous changes of EGF and EGFr in the bum wound
摘要
Abstract
Objective To observate the change and the distribution of endogenous epidermal growth factor (EGF) and epidermal growth factor recepter (EGFr) in the burn wound and their effects on the wound healing. Methods The immunohistochemistry stainning method is used to detect the expression of EGF and EGFr in the different parts of burn wound in 35 patients. Results There are more remarkably expression of EGF and EGFr in the margin part between the granulation part and the healed part of the burn wound and with obviously expression of EGF and EGFr in the center granulation part and with slightly expression of EGF and EGFr in the healed reepithelization part of the wound. Conclusion The changes of endogenous EGF and EGFr in the burn wound are closely related to the wound healing and which may have an important role effects on wound healing.关键词
烧伤创面/表皮生长因子/表皮生长因子受体/免疫组织化学Key words
burn wound/epidermal growth factor receptor(EGFr)/epidermal growth factor (EGFr)/ immunohistochemistry分类
医药卫生引用本文复制引用
谷廷敏,隋志甫,常冬青,石成方,赵志力..烧伤创面内表皮生长因子与表皮生长因子受体蛋白变化的临床研究[J].中国美容医学,2011,20(3):414-416,3.基金项目
国家自然科学基金资助课题(30973123) (30973123)