中国全科医学2011，Vol.14Issue(15)：1632-1634,3.
不同程度糖尿病足溃疡风险患者血浆胰岛素样生长因子1水平的变化及意义
Changes of Plasma Insulin Like Growth Factor 1 in Patients with Different Risks of Diabetic Foot Ulcers and Their Significance
王晓丽 1常向云 1孙侃1
作者信息
- 1. 832000,新疆石河子市,石河子大学医学院第一附属医院内分泌代谢科
- 折叠
摘要
Abstract
Objective To explore the changes of insulin like growth factor 1 ( IGF - 1 ) in patients with different risks of diahetic foot ulcers. Methods The clinical biochemical indices and plasma IGF - 1 levels were determined in 126 diabetic patients divided into groups high - risk ( n =25 ), moderate - risk ( n =32 ), mild - risk ( n = 30 ), non - risk ( n =39 ), and in control group ( n = 20 ). Results The levels of plasma IGF - 1 were significantly lower in diabetic groups than in control group ( P ＜0. 05 ), and in high - risk group than in groups mild - risk and non - risk ( P ＜ 0. 05 ). Plasma IGF - 1 was negatively correlated with courses of diseases, HhA1c , 24 h urine protein excretion ( P ＜ 0. 05 ). Conclusion The decrease of plasma IGF - 1 may increase the risk of diabetic foot ulcer.关键词
糖尿病,2型/糖尿病神经病变/胰岛素样生长因子1分类
医药卫生引用本文复制引用
王晓丽,常向云,孙侃..不同程度糖尿病足溃疡风险患者血浆胰岛素样生长因子1水平的变化及意义[J].中国全科医学,2011,14(15):1632-1634,3.
