国际医药卫生导报2011,Vol.17Issue(10):1229-1232,4.DOI:10.3760/cma.j.issn.1007-1245.2011.10.028
乙肝血清标志物模式与HBV-DNA含量的关系探讨
Correlation between HBV serological markers and HBV-DNA
摘要
Abstract
Objective To analyze the correlation between the lovel of HBV semiogloat markers and HBV-DNA.Mothods Serum samples of 800 patients from Xinyi Pepole's Hospital clinic department suffering HBV were detected by ELISA and HBV-DNA were detected by FQ-PCR.then analyze the correlation between HBV serological markers and HBV-DNA.Results The HBV-DNA was detoeted in some HBV serological markerg groups and each group was different in the result.HBsAg positive.such as HBsAg,HBeAg and Anti-HBc positive samples has higher amount of copies of HBV-DNA;the low level of HBV-DNA copies were detected in the group of HBsAg.HBeAg or Anti-HBe,Anti-HBo lmsitive; and the HBV-DNA copies rate is 2.98%in the single HBsAg positive.Among 120 HBe Ag positive samples.there were 118 HBV-DNA positive,the positive rate of HBV-DNA was 98.33%and the level of HBeAg positive wail correlated to HBV-DNA(r=0.993).Conclusion Both the detection of HBeAg and HBV-DNA cab reflect the active level of duplicate of HBV-M.The HBV-DNA level showed all obvious correlation to the HBeAg contend in Bera.关键词
乙型肝炎病毒/血清标志物/HBV-DNA/相关性Key words
HBV-M/HBV-DNA/Correlation引用本文复制引用
张海业,孙溯荫,韦兰..乙肝血清标志物模式与HBV-DNA含量的关系探讨[J].国际医药卫生导报,2011,17(10):1229-1232,4.