军医进修学院学报2011,Vol.32Issue(5):432-434,3.
HDL-C对2型糖尿病合并冠状动脉粥样硬化血管病变的影响
Effect of high density lipoprotein-C on type 2 diabetes mellitus accompanying coronary atherosclerosis
王晓娜 1刘宏斌 1张弢
1荆晶 1王国位1
作者信息
- 1. 解放军总医院,心内科,北京,100853
- 折叠
摘要
Abstract
Objective To analyze the effect of high density lipoprotein-C(HDL-C) on type 2 diabetes mellitus(DM) accompanying coronary atherosclerosis. Methods Two hundred and twenty-seven patients with type 2 DM diagnosed with coronary atherosclerosis by coronary arteriongraphy(CAG) and undergone CAG at least after 6 months were enrolled in this study. The patients were divided into group A and group B according to their HDL-C. HDL-C in patients of group A was increased or unchanged and decreased in patients of group B. Results The progression rate of coronary atherosclerosis was 20.6% in group A and 36.5% in group B(P<0.01). The incidence of angina pectoris was 12.2% in group A and 15.6% in group B(P<0.05). The target lesion revascularization was 1.5% in group A and 3.1% in group B(P<0.01). Conclusion HDL-C is an independent risk factor for coronary atherosclerosis in patients with type 2 DM.关键词
冠状动脉粥样硬化/高密度脂蛋白胆固醇/2型糖尿病/冠脉造影Key words
Coronary Atherosclerosis/ High Density Lipoprotein Cholesterol/ Type 2 Diabetes Mellitus/ Coronary Angiography分类
临床医学引用本文复制引用
王晓娜,刘宏斌,张弢
,荆晶,王国位..HDL-C对2型糖尿病合并冠状动脉粥样硬化血管病变的影响[J].军医进修学院学报,2011,32(5):432-434,3.