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HDL-C对2型糖尿病合并冠状动脉粥样硬化血管病变的影响

王晓娜 刘宏斌 张弢 荆晶 王国位

军医进修学院学报2011,Vol.32Issue(5):432-434,3.
军医进修学院学报2011,Vol.32Issue(5):432-434,3.

HDL-C对2型糖尿病合并冠状动脉粥样硬化血管病变的影响

Effect of high density lipoprotein-C on type 2 diabetes mellitus accompanying coronary atherosclerosis

王晓娜 1刘宏斌 1张弢 1荆晶 1王国位1

作者信息

  • 1. 解放军总医院,心内科,北京,100853
  • 折叠

摘要

Abstract

Objective To analyze the effect of high density lipoprotein-C(HDL-C) on type 2 diabetes mellitus(DM) accompanying coronary atherosclerosis. Methods Two hundred and twenty-seven patients with type 2 DM diagnosed with coronary atherosclerosis by coronary arteriongraphy(CAG) and undergone CAG at least after 6 months were enrolled in this study. The patients were divided into group A and group B according to their HDL-C. HDL-C in patients of group A was increased or unchanged and decreased in patients of group B. Results The progression rate of coronary atherosclerosis was 20.6% in group A and 36.5% in group B(P<0.01). The incidence of angina pectoris was 12.2% in group A and 15.6% in group B(P<0.05). The target lesion revascularization was 1.5% in group A and 3.1% in group B(P<0.01). Conclusion HDL-C is an independent risk factor for coronary atherosclerosis in patients with type 2 DM.

关键词

冠状动脉粥样硬化/高密度脂蛋白胆固醇/2型糖尿病/冠脉造影

Key words

Coronary Atherosclerosis/ High Density Lipoprotein Cholesterol/ Type 2 Diabetes Mellitus/ Coronary Angiography

分类

临床医学

引用本文复制引用

王晓娜,刘宏斌,张弢 ,荆晶,王国位..HDL-C对2型糖尿病合并冠状动脉粥样硬化血管病变的影响[J].军医进修学院学报,2011,32(5):432-434,3.

军医进修学院学报

OACSTPCD

2095-5227

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