武警医学2011，Vol.22Issue(4)：281-283,3.
替米沙坦联合吲达帕胺对老年高血压伴高尿酸血症患者尿酸的影响
Effect of telmisartan combined with indapamide on uric acid in elderly hypertensive patients with hyperuricemia
谢飞 1闫鲲 1韦婵 1刘宁 1杜稳斌 1李俊贤 1王娟 1党彦龙1
作者信息
- 1. 710054,西安,武警陕西总队医院肾脏科
- 折叠
摘要
Abstract
Objective To study the effect of telmisartan combined with indapamide on uric acid in elderly hypertensive patients. Methods 113 elderly hypertensive patients were randomly divided into three groups: the control group was given amlodipine (5 mg/d, n= 39), the telmisartan group took telmisartan( 80 mg/d, n= 38 ) alone, while the combined treatment group took telmisartan combined with indapamide (80 mg/15mg, n= 36). After three months of treatment, there blood pressure and serum uric acid were measured in the three groups. Results After three months, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were significantly decreased in the three groups compared with baseline ( all P ＜ 0.01 ), especially in the combined treatment group ( all P ＜0.05 ). The serum uric acid level decreased more significantly in the telmisartan group than in the control group ( P ＜ 0.05 ) , but there was no significant difference ( P ＞ 0.05 ) between the combined treatment group and the control group. Conclusions Telmisartan combined with indapamide significantly enhances the antihypertensive effect, and telmisartan can reduce the level of serum acid (BUA) in patients with essential hypertension, but the combined treatment reduces the effect of decreasing BUA.关键词
替米沙坦/吲达帕胺/高血压/高尿酸血症Key words
telmisartan/ indapamide/ hypertension/ hyperuricemia分类
医药卫生引用本文复制引用
谢飞,闫鲲,韦婵,刘宁,杜稳斌,李俊贤,王娟,党彦龙..替米沙坦联合吲达帕胺对老年高血压伴高尿酸血症患者尿酸的影响[J].武警医学,2011,22(4):281-283,3.
