军医进修学院学报2011，Vol.32Issue(5)：516-518,3.
VEGF、NF-кB/p50在不同分型涎腺多形性腺瘤中的表达及意义
Expression of VEGF and NF-K B/p50 in different types of polymorphous adenoma of salivary gland and its significance
赵坚 1张望群 2李金源3
作者信息
- 1. 开滦(集团)有限责任公司医院,头颈外科,唐山,063000
- 2. 华北煤炭医学院附属医院,口腔科,唐山,063000
- 3. 华北煤炭医学院,口腔系,唐山,063000
- 折叠
摘要
Abstract
Objective To study the expression of VEGF and NF- k B/p50 in cell-rich and matrix-rich polymorphous adenomas of salivary gland and it significance. Methods Expressions of VEGF and NF- k B/p50 in 10S patients with polymorphous adenomas of salivary gland were detected with SP immunohistochemistry staining. Results The expression level of VEGF and NF- κB/p50 was higher in cell-rich and matrix-rich polymorphous adenomas than in normal salivary gland(P<0.05). The expression of VEGF was positively correlated with that of NF- κB/p50. Conclusion The ability of polymorphous adenomas to form blood vessels and proliferation of cells increase with the increased number of cells in the tumor. Cell-rich polymorphous adenomas are easier to become malignant than matrix-rich polymorphous adenomas.关键词
血管内皮生长因子/核转录因子/多形性腺瘤/免疫组化Key words
Vascular Endothelial Growth Factor/ Nuclear Factor of Kappab/ Pleomorphic Adenoma/ Immunohistochemistry分类
医药卫生引用本文复制引用
赵坚,张望群,李金源..VEGF、NF-кB/p50在不同分型涎腺多形性腺瘤中的表达及意义[J].军医进修学院学报,2011,32(5):516-518,3.
