首页|期刊导航|中国神经再生研究(英文版)|Bilateral olfactory ensheathing cell transplantation promotes neurological function in a rat model of cerebral infarction
中国神经再生研究(英文版)2011,Vol.6Issue(13):983-987,5.DOI:10.3969/j.issn.1673-5374.2011.13.004
Bilateral olfactory ensheathing cell transplantation promotes neurological function in a rat model of cerebral infarction
Bilateral olfactory ensheathing cell transplantation promotes neurological function in a rat model of cerebral infarction
摘要
Abstract
In the present study, olfactory ensheathing cells were transplanted into the cortices of infarcted (infarct transplantation group), normal (normal transplantation group), and bilateral hemispheres (bilateral transplantation group). Olfactory ensheathing cells migrated to the infarct focus. The number of growth associated protein 43-positive cells and nerve fibers was slightly increased in the infarct area. These changes were more evident in the bilateral cortical transplantation group. Results demonstrated that transplanted olfactory ensheathing cells can migrate in rats with cerebral infarction. The olfactory ensheathing cells on the normal side can also promote neurological function. Bilateral cortical transplantation exhibited superior effects over unilateral transplantation.关键词
cerebral infarction/cell transplantation/olfactory ensheathing cells/neural regenerationKey words
cerebral infarction/cell transplantation/olfactory ensheathing cells/neural regeneration引用本文复制引用
Zhihua Yang,Wenli Sheng,Huiyong Shen,Qinghua Hou,Rui Li,Jinsheng Zeng,Ruxun Huang..Bilateral olfactory ensheathing cell transplantation promotes neurological function in a rat model of cerebral infarction[J].中国神经再生研究(英文版),2011,6(13):983-987,5.基金项目
the National Natural Science Foundation of China,No.39700048*,30271378* ()
a grant from Education Bureau of Guangzhou,No.61092* ()
a grant from Science and Technology Department of Guangdong Province,No.2009B030801354* ()