| 注册
首页|期刊导航|中国神经再生研究(英文版)|Bilateral olfactory ensheathing cell transplantation promotes neurological function in a rat model of cerebral infarction

Bilateral olfactory ensheathing cell transplantation promotes neurological function in a rat model of cerebral infarction

Zhihua Yang Wenli Sheng Huiyong Shen Qinghua Hou Rui Li Jinsheng Zeng Ruxun Huang

中国神经再生研究(英文版)2011,Vol.6Issue(13):983-987,5.
中国神经再生研究(英文版)2011,Vol.6Issue(13):983-987,5.DOI:10.3969/j.issn.1673-5374.2011.13.004

Bilateral olfactory ensheathing cell transplantation promotes neurological function in a rat model of cerebral infarction

Bilateral olfactory ensheathing cell transplantation promotes neurological function in a rat model of cerebral infarction

Zhihua Yang 1Wenli Sheng 1Huiyong Shen 1Qinghua Hou 1Rui Li 1Jinsheng Zeng 1Ruxun Huang1

作者信息

  • 折叠

摘要

Abstract

In the present study, olfactory ensheathing cells were transplanted into the cortices of infarcted (infarct transplantation group), normal (normal transplantation group), and bilateral hemispheres (bilateral transplantation group). Olfactory ensheathing cells migrated to the infarct focus. The number of growth associated protein 43-positive cells and nerve fibers was slightly increased in the infarct area. These changes were more evident in the bilateral cortical transplantation group. Results demonstrated that transplanted olfactory ensheathing cells can migrate in rats with cerebral infarction. The olfactory ensheathing cells on the normal side can also promote neurological function. Bilateral cortical transplantation exhibited superior effects over unilateral transplantation.

关键词

cerebral infarction/cell transplantation/olfactory ensheathing cells/neural regeneration

Key words

cerebral infarction/cell transplantation/olfactory ensheathing cells/neural regeneration

引用本文复制引用

Zhihua Yang,Wenli Sheng,Huiyong Shen,Qinghua Hou,Rui Li,Jinsheng Zeng,Ruxun Huang..Bilateral olfactory ensheathing cell transplantation promotes neurological function in a rat model of cerebral infarction[J].中国神经再生研究(英文版),2011,6(13):983-987,5.

基金项目

the National Natural Science Foundation of China,No.39700048*,30271378* ()

a grant from Education Bureau of Guangzhou,No.61092* ()

a grant from Science and Technology Department of Guangdong Province,No.2009B030801354* ()

中国神经再生研究(英文版)

OACSCD

1673-5374

访问量0
|
下载量0
段落导航相关论文