中国中西医结合杂志2011，Vol.31Issue(4)：483-486,4.
电针阳明经穴对急性脑梗死患者PAC-1表达及下肢功能恢复的影响
Effect of Electro-needling at Acupoints of the Yangming Meridian on the Expression of PAC-1 and Lower Limb Functions in Acute Cerebral Infarction Patients
摘要
Abstract
Objective To observe the effect of electro-needling at acupoints of the yangming meridian on the expression of platelet associated complement-1 ( PAC-1 ) and lower limb functions in acute cerebral infarction ( ACI ) patients. Methods 58 ACI patients were randomly assigned to the treatment group and the control group.Conventional therapies were given to all patients. Additionally, the electro-needling at acupoints of the yangming meridian was given to patients in the treatment group. Changes of PAC-1 were detected using flow cytometry.Effect of lower limbs functions of ACI patients before and after electro-needling was assessed using FugI-Meyer Index. Meanwhile, 20 healthy subjects were selected for reference value. Results In the acute stage, the PAC-1 level in ACI patients were significantly higher than that in healthy subjects ( P ＜0. 05). The PAC-1 level in the electro-needling group was obviously lowered after treatment ( P ＜ 0. 01 ). There was no significant difference in the control group between before and after treatment. Significant difference was found in FugI-Meyer index in the same group between before and after two-week treatment ( P＜0. 05). It was higher in the electro-needling group than in the control group, showing significant difference (P ＜0.01 ). Conclusions Platelet activation exists in the acute stage of ACI. Electro-needling at acupoints of the yangming meridian showed obvious inhibition on PAC-1 levels, could improve lower limbs functions of ACI patients. It was inferred that electro-needling at acupoints of the yangming meridian promoted the recovery of paralyzed lower limbs at the early stage mainly by regulating PAC-1 levels, thus postponing the progress of ACI.关键词
电针/阳明经穴/急性脑梗死/血小板膜糖蛋白纤维蛋白原受体/下肢功能Key words
electro-needling/ acupoints of the yangming meridian/ acute cerebral infarction/ platelet associated complement-1/ lower limb function引用本文复制引用
张炘,谭峰,段传志,方美凤,黄彪,龙霄翱,罗斌..电针阳明经穴对急性脑梗死患者PAC-1表达及下肢功能恢复的影响[J].中国中西医结合杂志,2011,31(4):483-486,4.基金项目
广东省医学科学技术研究基金项目(No.WSTJJ20051101430103590927157) （No.WSTJJ20051101430103590927157）
