解放军医学杂志2011，Vol.36Issue(4)：319-322,4.
脉压、脉压指数对冠心病的预测价值及其与冠状动脉病变严重程度的相关性分析
Pulse pressure and pulse pressure index: prediction for and correlation with the severity of coronary artery lesion in patients with coronary artery disease
摘要
Abstract
Objective To investigate the correlation between pulse pressure (PP), pulse pressure index (PPI) and the severity of coronary artery lesion in patients with CAD, and evaluate the significance of PP and PPI in predicting CAD. Methods The data of 9847 patients who had undergone coronary angiography were collected. The positive coronary angiography (stenosed major vessels ≥ 50％)served as a diagnostic standard of CAD. CAD severity was assessed by Gensini score, and the number of stenosed arteries was counted.Relationship between PP, PPI and the severity of CAD was evaluated by both single factor analysis and multivariate binary logistic regression analysis. Results The CAD patients were found to have higher PP (54.63±15.82 vs 49.74±14.27, P＜0.001) and PPI (0.40±0.07 vs 0.38±0.07, P＜0.001). Furthermore, the severity of CAD were associated with increased PP and PPI. Binary logistic regression analysis showed that PPI was a prominent predictor of the CAD ( OR=4.921,95％CI 2.241～10.808, P＜0.001). Conclusion The levels of PP and PPI are significantly correlated with CAD: PPI is the most prominent predictor in diagnosis of CAD.关键词
血压/脉压指数/冠状动脉疾病/危险因素分类
医药卫生引用本文复制引用
张磊,韩雅玲,荆全民,王效增,李毅,鄢高亮,关绍义,霍勇,张岩..脉压、脉压指数对冠心病的预测价值及其与冠状动脉病变严重程度的相关性分析[J].解放军医学杂志,2011,36(4):319-322,4.基金项目
"十一五"国家科技支撑计划项目(2006BAI01A02) （2006BAI01A02）
