解放军医学杂志2011，Vol.36Issue(4)：336-339,4.
2型糖尿病与绝经后女性冠心病患者冠状动脉狭窄程度的相关性分析
Correlation between type 2 diabetes and the degree of coronary artery stenosis in postmenopausal women with coronary artery disease
摘要
Abstract
Objective To evaluate the correlation between multiple cardiovascular risk factors and the severity of coronary artery lesions in young patients (age ≤45 years). Methods One thousand one hundred and thirty-seven patients who had undergone coronary angiography were selected according to founded criteria. Of them 494 were diagnosed as coronary artery disease (CAD group) and 643 as non-CAD (non-CAD group) by angiography. The difference of the risk factors between the two groups, and the characteristics of coronary artery lesions revealed by the severity of coronary artery lesion, Gensini cumulative score, and number of stenosed coronary artery branches, were analyzed. Results Obvious differences were found between the two groups in regard to sex ratio, incidence of hypertension, type Ⅱ diabetes and obesity, and the habit of smoking and drinking. Logistic regression analysis showed that type Ⅱ diabetes was the most significant predictor for the extent and severity of CAD in young patients, followed by hypertension and low density lipoprotein-cholesterol (LDL-C). The serum level of total bilirubin was the protective factor of CAD. Conclusion The most important independent risk factor for CAD in young patients is type Ⅱ diabetes mellitus, and the independent protective factor is the serum level of total bilirubin.关键词
动脉粥样硬化/冠状动脉疾病/糖尿病,2型/绝经后期/Gensini积分分类
医药卫生引用本文复制引用
鄢高亮,韩雅玲,荆全民,王效增,李毅,张磊,关绍义,霍勇,张岩..2型糖尿病与绝经后女性冠心病患者冠状动脉狭窄程度的相关性分析[J].解放军医学杂志,2011,36(4):336-339,4.基金项目
"十一五"国家科技支撑计划项目(2006BAI01A02) （2006BAI01A02）
