中国实验动物学报2011,Vol.19Issue(2):161-171,11.DOI:10.3969/j.issn.1005-4847.2011.02.016
鼠疫动物模型:经典与问题
Animal model of plague: classics and questions
摘要
Abstract
The research on Yersinia pestis greatly focuses on the pathogenetic mechanism, vaccines and treatments.Effective animal models of plague are the basis of these researches.Numerous types of animal models of plague have been developed, including mice, guinea pigs and non-human primates, etc., and they are useful for understanding, defending and treating this disease.Some classic models are still used at present for different purposes, however, others were discarded because of certain problems.The advantages and disadvantages of different animal models of plague are summarized and discussed in this review.关键词
鼠疫菌/模型,动物/致病机制/疫苗分类
生物科学引用本文复制引用
毕玉晶,杨瑞馥..鼠疫动物模型:经典与问题[J].中国实验动物学报,2011,19(2):161-171,11.基金项目
中国科学院病原微生物与免疫学重点实验室开放课题资助(No.2009CASPMI-001). (No.2009CASPMI-001)