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高效液相色谱法测定小儿早熟抗胶囊中栀子苷含量

郑国平 李彬

中国药业2011,Vol.20Issue(8):34-35,2.
中国药业2011,Vol.20Issue(8):34-35,2.

高效液相色谱法测定小儿早熟抗胶囊中栀子苷含量

Determination of Geniposide in Xiao'er Zaoshukang Capsule by HPLC

郑国平 1李彬1

作者信息

  • 1. 浙江省舟山市食品药品检验所,浙江,舟山,316000
  • 折叠

摘要

Abstract

Objective To develop a HPLC method for the determination of geniposide in Xiso'er Zaoshoukang Capsule. Methods The Eclipse-C18 column(250 mm ×4.6 mm, 5 μm) was used with the mobile phase of acetonitrile-water(12: 88), the flow rate of 1.0 mL/min and the detection wavelength of 238 nm. Results The good linear relationship for geniposide was in the ranges of 3.625-580.0 μg/mL( r = 1. 000 0, n =7). The average recovery rate was 97.91%, RSD = 1.33% ( n =9). Conclusion This HPLC method is simple, quick,rapids and accurate, which can be used for the quality control of xiao'er zaoshukang capsule.

关键词

小儿早熟抗胶囊/栀子苷/高效液相色谱法/含量测定

分类

医药卫生

引用本文复制引用

郑国平,李彬..高效液相色谱法测定小儿早熟抗胶囊中栀子苷含量[J].中国药业,2011,20(8):34-35,2.

基金项目

浙江省中医药科技计划项目,项目编号:2008JA010. ()

中国药业

OACSTPCD

1006-4931

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