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服用阿托伐他汀的不稳定型心绞痛患者血清LDL-C达标率的影响因素

于薇 孟存良 容春莉 曹东平 吕军娥 彭应心

重庆医学2011,Vol.40Issue(16):1588-1590,3.
重庆医学2011,Vol.40Issue(16):1588-1590,3.DOI:10.3969/j.issn.1671-8348.2011.16.011

服用阿托伐他汀的不稳定型心绞痛患者血清LDL-C达标率的影响因素

Influence factors of success rate of serum LDL-C in patients with unstability angina pectoris taking atorvastatin

于薇 1孟存良 1容春莉 1曹东平 1吕军娥 1彭应心1

作者信息

  • 1. 河北省人民医院心血管内科,河北石家庄,050051
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摘要

Abstract

Objective To analyze the clinical influence factors of success rate of serum low density lipoprotein-cholesterol(LDL-C) in patients with unstability angina pectoris taking aorvastatin. Methods 146 patients with unstability angina pectoris and unsuccessful level of serum LDL-C were collected. 20 mg atorvastatin were taken orally once a day with treatment course of 8 weeks.Effects of clinical factors such as age, gender, body mass index(BMI), diet control and glycosylated hemoglobin Alc (HbAlc) on success rate of serum LDL-C after aorvastatin administration were analyzed. Results The overall success rate of serum LDL-C was 49.3 % after 8 weeks of aorvastatin administration;Age had no significant correlation with the success rate of LDL-C according to stepwise multivariate Logistic regression analysis;Comparison of the success rates of LDL-C among BMI normal group,overweight group and obesity group,there were no statistically significant(P>0.05) ;Success rates of LDL-C of patients in diet control group were higher than that in non-diet control group;Patients with well-controlled blood glucose showed higher success rates of LDL-C.Conclusion Control levels of diet and blood glucose are independent influence factors of success rate of LDL-C in patients with unstability angina pectoris taking atorvastatin.

关键词

心绞痛,不稳定型/血糖/低密度脂蛋白-胆固醇/阿托伐他汀

Key words

angina/ unstable/ blood glucose/ low density lipoprotein-cholesterol/ atorvastatin

引用本文复制引用

于薇,孟存良,容春莉,曹东平,吕军娥,彭应心..服用阿托伐他汀的不稳定型心绞痛患者血清LDL-C达标率的影响因素[J].重庆医学,2011,40(16):1588-1590,3.

重庆医学

OA北大核心CSCDCSTPCD

1671-8348

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