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石墨炉原子吸收分光光度法测定阿莫西林胶囊中微量铅、镉的含量

杨大勇 余敏灵

中国药房2011,Vol.22Issue(16):1519-1520,2.
中国药房2011,Vol.22Issue(16):1519-1520,2.

石墨炉原子吸收分光光度法测定阿莫西林胶囊中微量铅、镉的含量

Content Determination of Lead and Cadmium in Amoxicillin Capsules by Graphite Furnace Atomic Absorption Spectrometry

杨大勇 1余敏灵1

作者信息

  • 1. 四川武警总队医院,乐山市,614000
  • 折叠

摘要

Abstract

OBJECTIVE: To establish method for the content determination of trace lead and cadmium in Amoxicillin capsules.METHODS: Graphite furnace atomic absorption spectrometry (GFAAS) was adopted. The determination wavelength was set at 283.3 nm for lead, 228.8 nm for cadmium. The lamp current was 2.0 mA and the slit-width was 0.4 nm. RESULTS: The linear range of was 0~10.0 ng·mL-1 for lead and 0~0.5 ng·mL-1 for cadmium. The average recoveries were 98.0% (RSD=1.0%, n=9) and 97.8% (RSD=0.99%, n=9), respectively. CONCLUSION: GFAAS is accurate, simple and sensitive for content determination of lead and cadmium in Amoxicillin capsules.

关键词

石墨炉原子吸收分光光度法/含量测定/阿莫西林胶囊//

Key words

Graphite furnace atomic absorption spectrometry/ Content determination/ Amoxicillin capsules/ Lead/ Cadmium

分类

医药卫生

引用本文复制引用

杨大勇,余敏灵..石墨炉原子吸收分光光度法测定阿莫西林胶囊中微量铅、镉的含量[J].中国药房,2011,22(16):1519-1520,2.

中国药房

OACSCDCSTPCD

1001-0408

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