现代妇产科进展2011，Vol.20Issue(4)：283-285,289,4.
不同促排卵方案在多囊卵巢综合征患者IVF-ET治疗中的应用分析
An analysis of different protocols of controlled ovarian hyperstimulation applied in patients with PCOS for in vitro fertilization and embryo transfer
王力 1闻姬 1崔薇 1孙伟1
作者信息
- 1. 山东中医药大学第二附属医院生殖中心,济南,250001
- 折叠
摘要
Abstract
Objective : To investigate the clinic effect of IVF-ET in patients with PCOS who were undergoing long GnRH agonist protocol ( group 1 = 58) . short CnRH agonist protocol ( group 2 = 52) , GnRH antagonists protocol( group 3 = 41 ) . Methods : 151 cycles with PCOS undergoing IVF-ET between January 2008 and June 2010 were enrolled in this study to the clinical characteristics of patients; the duration of gonadotrophin administration, total dose of gonadotrophin , the level of LH , P, E2 on HCC day, fertilization rate , the rat of high-quality embryo,pregnancy rate , cycle-cancellation rate, OHSS incidence rate. Results : No significant difference was found in the clinical characteristics among Lhe 3 groups( P＞0. 05 ) There was a significant difference in the duration of gonadotrophin administration and total dose of gonadotrophin among Uoups ( P＜O. 05 ) . The fertilization rate , the rate of high-quality embryo, abortion rate were also no different among groups. Pregnancy rate in group Ⅲ was the highest ( P＜0. 05) . There was a significant difference in the cycle-cancellation rate and OHSS incidence between group Ⅲ and other 2 groups ( P＜0. 05 ) . Conclusion : In PCOS patients undergoing IVF-ET , CnRH-A administration shorten the duration of gonadotrophin administration and dose of gonadotrophin, increase the pregnancy rate , reduce the cycle-cancellation rate and OHSS incidence, and ease the financial burden of patients as well. Besides,it is considered as a relatively appropriate protocol for patients with PCOS.关键词
多囊卵巢综合征/GnRH激动剂/GnRH拮抗剂/体外受精-胚胎移植分类
医药卫生引用本文复制引用
王力,闻姬,崔薇,孙伟..不同促排卵方案在多囊卵巢综合征患者IVF-ET治疗中的应用分析[J].现代妇产科进展,2011,20(4):283-285,289,4.
