临床肝胆病杂志2011，Vol.27Issue(4)：378-381,4.
肝癌分期对肝动脉化疗栓塞术后生存的预测作用
Prognostic accuracy of staging systems in patients with primary liver cancer treated with transarterial chemoembolization
摘要
Abstract
Objective To compare the performance of 6 available prognostic staging systems in predicting the survival of patients with primary liver cancer treated with TACE.Methods The clinical data of patients who had been diagnosed as liver cancer in our department from September 2006 to May 2009 were retrospectively analyzed to compare the CTP classification, the MELD scoring,the BCLC classification system, the CS staging system and the Tokyo scoring.Results The survival curves and log-rank test shows statistical significance in all stages of the Okuda staging system( Ⅰ vs Ⅱ P=0.013, Ⅱ vs Ⅲ P＜0.001), between stage B and C of the BCLC classification system (P=0.008) and between stage Ⅱ and Ⅲ of the CS staging system (P=0.001).By the multiple factor regression method, the Okuda staging system (P=0.039) and the BCLC classification (P=0.022) also show a stronger significance on the prognosis.And the BCLC classification system is superior to the other staging systems with the minimum value of-2Ln(L) (205.419), AIC (209.419),SBC (212.586).Conclusion The BCLC classification system provides the best prognostic stratification for a cohort of the patients with liver cancer treated with transarterial chemoembolization.关键词
肝肿瘤/肝动脉/化学栓塞,治疗性Key words
liver neoplasms/ hepatic artery/ chemoembolizatior/ therapeutic分类
医药卫生引用本文复制引用
张峰,诸葛宇征,仇毓东,黄新,李振磊,张建武..肝癌分期对肝动脉化疗栓塞术后生存的预测作用[J].临床肝胆病杂志,2011,27(4):378-381,4.基金项目
国家传染病防治科技重大专项--肝癌的精确TACE治疗子课题(008zx10002-26) （008zx10002-26）
