中国肺癌杂志2011，Vol.14Issue(4)：345-350,6.DOI:10.3779/j.issn.1009-3419.2011.04.08
工作环境烟草暴露与肺癌发生危险的系统评价
Systematic Review of Studies of Workplace Exposure to Environmental Tobacco Smoke and Lung Cancer Risk
王新卓 1秦玉坤 1谷俊东 2王凤玮 1贾培杰 1王辉 1姚嫱 1朱思伟1
作者信息
- 1. 300121,天津,天津市人民医院肿瘤科
- 2. 300121,天津,天津市人民医院胸外科
- 折叠
摘要
Abstract
Background and objective It has been reported that there was a close relationship between lung cancer risk and environmental tobacco smoke at workplace.The aim of this study is to explore the relationship between workplace environmental tobacco smoke exposure and lung cancer risk among non-smoking subjects.Methods By searching Medline,CENTRAL (the Cochrane central register of controlledtrials), EMBASE, CBM, CNKI and VIP et at, we collected both domestic and overseas published documents on workplace environmental tobacco smoke exposure and lung cancer risk.Random or fixed effect models were applied to conduct systematic review on the study results, the combined odds ratio (OR) and the 95％ confidence interval (CI) were calculated as well.Results 22 reports were included into the combined analysis, which indicated that 25％ lung cancer risk was increased by exposing to workplace environment tobacco smoke (OR=1.25, 95％CI:1.13-1.39, P＜0.001).For female the increased risk was 22％ (OR=1.22, 95％CI: 1.05-1.42, P=0.011).For male the increased risk was 54％, but it does not reach the statistical significance (O R= 1.54, 95％ CI: 0.74-3.18, P=0.247).Conclusion Workplace environmental tobacco smoke exposure is an important risk factor of lung cancer risk among non-smoking subjects.Especially for non-smoking women who exp ose to workplace environment tobacco smoke have a close relationship with lung cancer.关键词
肺肿瘤/环境/烟草/系统评价Key words
Lung neoplasms/ Environment/ Tobacco/ Systematic review分类
医药卫生引用本文复制引用
王新卓,秦玉坤,谷俊东,王凤玮,贾培杰,王辉,姚嫱,朱思伟..工作环境烟草暴露与肺癌发生危险的系统评价[J].中国肺癌杂志,2011,14(4):345-350,6.
