中国药业2011,Vol.20Issue(9):31-32,2.
连翘滴眼液的制备与质量控制
Preparation and Quality Control of Forsythia Suspensa Eye Drops
兰鸿 1陈鸿梅1
作者信息
- 1. 湖北医药学院附属太和医院,湖北,十堰,442000
- 折叠
摘要
Abstract
Objective To prepare Forsythia suspensa Eye Drops and establish it's quality control method.Methods Alcohol extracting-water precipitating method is applied to extract the effective ingredient as primary medicine, while borax, boric acid, ethyl hydroxybenzoate is applied as excipient for the preparation of Forsythia suspense Eye Drops.The content of forsythin in the agent is determined by HPLC, as well as the observation of stability and pharmacodynamics.The eye drops' quality control is on the basis of Chinese Pharmacopoeia.Results In the density range of 20- 200 μg/mL, the linear relation is good( r = 0.999 9), the average recovery rate is 99.53%, RSD is 1.51%(n = 6).Conclusion The methods is rational and controllable.关键词
连翘滴眼液/制备/连翘苷/高效液相色谱法/质量控制分类
医药卫生引用本文复制引用
兰鸿,陈鸿梅..连翘滴眼液的制备与质量控制[J].中国药业,2011,20(9):31-32,2.