中国药业2011，Vol.20Issue(9)：58-59,2.
含微生态制剂的四联疗法治疗初治失败的幽门螺杆菌感染31例
Effect of Quadruple Therapy Containing Microecologics on Helicobacter Pylori Infection after First Treatment Failure in 31 Cases
摘要
Abstract
Objective To observe the effects and adverse reactions of quadruple therapy with microecologics supplementation on Helicobacter pylori(HP) infection after first treatment failure.Methods Sixty- two cases of HP eradication failure were divided into two groups randomly, group A treated with rabeprazole + furazolidone + amoxillin + colloidal bismuth pectin and group B with rabeprazole + furazolidone + amoxicillin + microecologics, the treatment course was 7 d in both groups.The eradication of HP was redetermined by the 14C- urea breath test in 4 weeks after treatment.Results The eradication rate was 79.31％ in group A and 83.33％ in group B respectively(P＞0.05).The gastrointestinal adverse reactions in group B were fewer than those in group A( P ＜ 0.05).Conclusion The quadruple therapy containing microecologics is effective in HP infection eradication after first treatment failure, furthermore, which may obviously reduce the adverse reactions in the treatment course.关键词
微生态制剂/幽门螺杆菌/四联疗法分类
医药卫生引用本文复制引用
周刚,李之印,王仲略,沈慧琳..含微生态制剂的四联疗法治疗初治失败的幽门螺杆菌感染31例[J].中国药业,2011,20(9):58-59,2.基金项目
浙江省自然科学基金项目,项目编号:Y0280675. （）
