厦门大学学报（自然科学版）2011，Vol.50Issue(2)：431-436,6.
戊型病毒性肝炎研究进展
Recent Progress in Hepatitis E
摘要
Abstract
Hepatitis E is one af the most important viral hepatitis in the world. Lots of large scale hepatitis E outbreaks occurred in recent half century, in which the mortality rate is as high as 20 ％ in pregnant women. With the successfully development of conformational polypeptide E2-based diagnostic reagents, clinical diagnosis and epidemiology study of hepatitis E progressed greatly. The recombinant hepatitis E vaccine developed by Chinese scientists has successfully finished phase Ⅲ clinical trial in China,which is the first phase Ⅲ clinical trial in the world, vaccine efficacy after 3 doses is 100 ％ (95 ％ CI,72. 1％ to 100. 0 ％).关键词
戊型病毒性肝炎/戊型肝炎病毒/E2/诊断试剂/重组戊型肝炎疫苗Key words
hepatitis E/ hepatitis E virus/ E2 / diagnostic reagents/ recombinant hepatitis E vaccine分类
医药卫生引用本文复制引用
夏宁邵,张军,李少伟,葛胜祥,吴婷,郑子峥,吴文翰,史维国..戊型病毒性肝炎研究进展[J].厦门大学学报（自然科学版）,2011,50(2):431-436,6.基金项目
国家高技术研究发展计划(863)重点项目(2006AA02A209) （863）
国家自然科学杰出青年基金(30925030) （30925030）
传染病重大专项(2009ZX10004-704) （2009ZX10004-704）
国家自然科学基金项目(30870514) （30870514）
