中国临床药理学与治疗学2011，Vol.16Issue(3)：313-316,4.
131I治疗Graves病的疗效及相关因素的回顾性分析
Effects of Idine-131 therapy of Graves disease and some correlative factors
谢彦 1吴克芳 1罗芙蓉 1徐泉凤 1杨军 1黄智慧 1王超群 1程光华1
作者信息
- 1. 皖南医学院弋矾山医院核医学科,芜湖,241001,安徽
- 折叠
摘要
Abstract
AIM: To retrospectively analysis the clinical effect of 131I therapy of Graves disease and some correlative factors. METHODS:The effects of some factors which including gender,age,thyroid weight and 131I dose on the cure rate and the incidence rate of hypothyroidism were observed,through the follow-up of 406 cases between 12 and 29 months of 131I therapy of patients with Graves disease in our hospital, RESULTS:406 patients,the follow-up showed that the therapy was recovered in 248(61.08％), effective 155(38.18％),became hypothyroidism in 118 (29.06％), failure in 3 (0.74％). Totally,99.26 ％ patients were responsed to the intervention. The gender and age were no significant difference to the incidence rate of hypothyroidism and cure rate after 131I in the initial treatment of Graves disease (P ＞ 0.05). Thyroid weight and dose of 131I showed significant difference to the incidence rate of hypothyroidism and cure rate ( P ＜ 0.01 ). CONCLUSION: Idine-131 therapy is preffered for patients with graves disease because of being efficient, convenient and secure. The difference of thyroid weight and dose of 131I do significant influence to the incidence rate of hypothyroidism and cure rate.关键词
Graves病/131I/治愈率/甲减发生率Key words
Graves disease/ 131I/ Incidence rate of hypothyroidism/ Cure rate分类
医药卫生引用本文复制引用
谢彦,吴克芳,罗芙蓉,徐泉凤,杨军,黄智慧,王超群,程光华..131I治疗Graves病的疗效及相关因素的回顾性分析[J].中国临床药理学与治疗学,2011,16(3):313-316,4.
