中国比较医学杂志2011，Vol.21Issue(5)：37-40,后插4,5.DOI:10.3969/j.issn.1671.7856.2011.05.009
大鼠肾移植慢性排斥反应模型的建立
Establishment of Rat Renal Transplantation Model of Chronic Rejection
摘要
Abstract
Objective To establish stable and reliable rat renal transplantation models of chronic rejection.Methods Wistar and SD rats were used as donors and recipients, left renal was removed from the donors. End-to-end anastomosis of inferior vena cava and renal vein, abdominal aorta and renal artery were operated. At 3, 6, 9 weeks, renal allografts were removed and postoperative complications and renection were observed. Results At 9 weeks, visible chronic rejection could be seen and some allograts suffered from hydronephrosis, while which had little relationship with rejection.Conclusions This method is feasible and reliable for chronic rejection of rat and it is an ideal model.关键词
肾移植/模型,动物/大鼠/慢性排斥反应分类
医药卫生引用本文复制引用
赵亚昆,祝清国,陈剑峰,仇宇,于忠浩..大鼠肾移植慢性排斥反应模型的建立[J].中国比较医学杂志,2011,21(5):37-40,后插4,5.基金项目
哈尔滨市科技攻关计划项目(2005AA9CS1168) （2005AA9CS1168）
黑龙江省科技攻关项目(GC06C40802) （GC06C40802）
哈尔滨医科大学附属第二医院博士科研基金项目(BS2007-25). （BS2007-25）
