首页|期刊导航|中国神经再生研究（英文版）|Identification of the primary motor area by three-dimensional reconstruction of the corticospinal tract using diffusion tensor imaging
中国神经再生研究（英文版）2011，Vol.6Issue(14)：1103-1107,5.DOI:10.3969/j.issn.1673-5374.2011.14.012
Identification of the primary motor area by three-dimensional reconstruction of the corticospinal tract using diffusion tensor imaging
Identification of the primary motor area by three-dimensional reconstruction of the corticospinal tract using diffusion tensor imaging
摘要
Abstract
Functional MRI (fMRI) is widely used as a non-invasive method for the evaluation of pre-operation motor function. However, patients with cortical function impairment, such as those with hemiparesis, can rarely achieve hand clenching, a typical fMRI task for central sulcus identification, and the method is also of limited use in uncooperative children. Thus, it is important to develop a new method for identifying primary motor areas (PMA) in such individuals. This study used corticospinal tractography to identify the PMA in 20 patients with deep-seated brain tumor. Two regions of interest were set within the brainstem for corticospinal tract (CST) fiber tracking: one at the level of the pons and the other at the level of the cerebral peduncle. The CST fiber tracking results and fMRI activation signals were merged with three-dimensional anatomic MRI findings. The consistency of identifying the PMA by CST and fMRI was analyzed. fMRI activation signals were distributed mainly in the contralateral central sulcus around the omega-shaped hand knob. The CST consistently propagated from the pons and cerebral peduncle to the suspected PMA location. There was a good correlation between CST fiber tracking results and fMRI activation signals in terms of their abilities to identify the PMA. The differences between fMRI and CST fiber tracking findings may result from our functional task, which consisted only of hand movements. Our results indicate that diffusion tensor imaging is a useful brain mapping technique for identifying the PMA in paralyzed patients and uncooperative children.关键词
diffusion tensor imaging/diffusion tensor tractography/primary motor area/functional magnetic resonance imaging/tractographyKey words
diffusion tensor imaging/diffusion tensor tractography/primary motor area/functional magnetic resonance imaging/tractography引用本文复制引用
Guojun Deng,Luo Li,Guimei Chen,Erming Zeng,Xiangzuo Xiao,Meihua Li,Tao Hong,Donghai Li..Identification of the primary motor area by three-dimensional reconstruction of the corticospinal tract using diffusion tensor imaging[J].中国神经再生研究（英文版）,2011,6(14):1103-1107,5.基金项目
the Science and Research Project of Jiangxi Provincial Department of Science and Technology,No.07-1012 （）
a grant from the Jiangxi Provincial Department of Education,No.GJJ08116 （）
