中国药理学通报2011,Vol.27Issue(7):903-906,4.DOI:10.3969/j.issn.1001-1978.2011.07.005
内源性大麻素系统对心血管功能的调节作用
The endocannabinoid system in regulation of cardiovascular functions
摘要
Abstract
The endocannabinoid exerts various cardiovascular effects such as vasorelaxation, lower blood pressure and negative inotropic effects via multiple signaling transduction by its receptor dependent and independent pathway. It is also involved in antiinflammatoryand endothelial-protecting effects. Therefore, the research on the pharmacological mechanism of the endocannabinoid system( ECS ) may play an important role in treatment of hypertension, atherosclerosis, myocardial ischemia reperfusion injury and heart failure.关键词
内源性大麻素/大麻素受体/信号传导/心脏/血管/心血管疾病分类
医药卫生引用本文复制引用
周广海,金松南,文今福..内源性大麻素系统对心血管功能的调节作用[J].中国药理学通报,2011,27(7):903-906,4.基金项目
国家自然科学基金资助项目(No 30971080) (No 30971080)
山东省自然科学基金资助项目(No ZR2009CM040) (No ZR2009CM040)